The stability and reactivity of isothiocyanates and the plausible behavior of their dithiocarbamate- and thiourea-conjugates

Isothiocyanates (ITCs) are organosulfur compounds derived from cruciferous plants. An electrophilic ITC group (-N=C=S) reacts with some functional groups such as a hydroxyl ion, thiol and amine in proteins. It is known that ITCs decomposed easily by the addition of ion to aqueous solutions. In intracellular behavior, primary target group, which results formation their dithiocarbamate conjugates. The reaction considered induce health promoting disease preventive effects ITCs. also react form stable thioureas. This review offers short summary stability reactivity plausible behavior dithiocarbamate- thiourea-conjugates.